The Jets head to MetLife for a key Week 2 clash with Buffalo after Week 1 chaos. New York fell 34-32 to Pittsburgh on a late Chris Boswell field goal, while Buffalo survived Baltimore 41-40 in a wild finish. This matchup could tilt the AFC East early, highlighting Jets’ improving secondary and Bills’ late-game firepower as the primary fantasy drivers.

Fantasy angles center on defensive progress, potential turnover opportunities from the Jets’ secondary, and Bills’ ability to close in the fourth. Expect a measured pace with high-stakes red-zone plays; the winner may own an early edge in the division, making Week 2 a marquee event for rosters and DFS lineups.

Week 2 fantasy and betting guide spotlights a slate rich in NFC/DIV rivalries, a short-week test for Washington in Green Bay, and a QB swap that could shift SF’s fantasy landscape. Jayden Daniels’ multi‑dimensional presents a new stress test for the Packers’ front, while the Rams’ pass rush and a banged‑up SF offense shape a few must‑buy and fade calls for fantasy lineups and prop bets.

Key matchups loom: Bills at Jets, Bengals at Jaguars, and a Bucs‑Texans clash that leans defense and run game. The latest injury news—Purdy’s turf toe and Jones’ Indy resurgence—could tilt Week 2 upside toward explosive receivers and run‑heavy schemes. Managers should lean into high‑volume roles, monitor QBs’ health, and target offenses with clear functional roles in favorable spots.

Bottom line for fantasy: chase safe volume in the games expected to stay competitive, target matchup-advantaged receivers, and be ready to pivot on late-week injury news. Week 2 offers multiple opportunities to deploy mid-round values and streaming options with clear upside in primetime and Sunday slots.

Palmer’s Week 2 outlook is cautious after Week 1’s 61 receiving yards on 9 targets. With Keon Coleman and Khalil Shakir healthy, Palmer’s target volume is volatile and touchdown-dependent, leaving him as a shaky FLEX in PPR. Against the Jets, expect a low floor unless Bills funnel extra looks due to injuries.

In standard leagues, Palmer remains a sit. In full-PPR formats, he’s a speculative flex unless injuries push more targets his way. Hold only if you’re chasing depth or if Coleman's or Shakir’s availability isn’t certain.